Novel method to accurately measure key marker of biological aging dukenus NatureComms
, our established method will allow for the interpretation of phenotypes in a small and controlled study settings to evaluate the effects of potential interventions on the steady-state telomere maintenance in patients.
Antecubital venous blood samples were taken from consenting participants and stored in PAXgene blood DNA tube . We used fresh or archived samples in the current study. For fresh samples, after collection, the blood samples were immediately processed. For archived samples, after collection, the blood samples were immediately placed on ice for transportation and were processed within 6 h to obtain buffy coat samples, which were subsequently stored at −80 °C.
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